SOLPRANZ -20

Vonoprazan is a novel potassium-competitive acid blocker (P-CAB). Mainly works by competitively binding to the H+/K+-ATPase on gastric acid-secreting cells, preventing hydrogen ions from entering the gastric activity, thereby inhibiting gastric acid secretion. Compared with proton pump inhibitors, it has a faster onset of action, stronger acid suppression and a longer duration of action. As not being affected by the physiological rhythm of gastric acid secretion, it can be administered at any time, without being limited to before or after meals. Due to longer half-life of vonoprazan, its efficacy lasts for a period of time, helping to reduce the daily dosage.